Crystal structure and catalytic activity of the PPM1K N94K mutant

Author:

Dolatabad Meisam Rostaminasab1,Guo Lu-lu1,Xiao Peng12,Zhu Zhongliang3,He Qing-tao1,Yang Du-xiao1,Qu Chang-xiu1,Guo Sheng-chao1,Fu Xiao-lei1,Li Rui-rui1,Ge Lin1,Hu Ke-jia1,Liu Hong-da14,Shen Yue-mao2,Yu Xiao5,Sun Jin-peng16ORCID,Zhang Peng-ju1

Affiliation:

1. Key Laboratory Experimental Teratology of the Ministry of Education; Department of Biochemistry and Molecular Biology; Shandong University School of Medicine; Jinan Shandong China

2. Key Laboratory of Chemical Biology; Ministry of Education; Shandong University School of Pharmaceutical Science; Jinan Shandong China

3. School of Life Sciences; University of Science and Technology of China; Hefei Anhui China

4. Department of Pharmacology and Chemical Biology; School of Medicine; University of Pittsburgh; Pittsburgh Pennsylvania USA

5. Department of Physiology; Shandong University; School of Medicine; Jinan Shandong China

6. Department of Physiology and Pathophysiology; School of Basic Medical Sciences; Peking University; Key Laboratory of Molecular Cardiovascular Science; Ministry of Education; Beijing China

Funder

Key Research and Development Program of Shandong Province

Rolling program of ChangJiang Scholars and Innovative Research Team in University

Shandong Natural Science Fund

Shandong Natural Science Fund for Distinguished Young Scholars

National Natural Science Foundation of China

China Postdoctoral Science Foundation

Shandong University

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience,Biochemistry

Reference46 articles.

1. Towards automated crystallographic structure refinement with phenix.refine;Afonine;Acta Crystallographica Section D,2012

2. BCAA Metabolism and NH3 Homeostasis;Conway;Advan. Neurobiol.,2016

3. Screening for replication of genome-wide SNP associations in sporadic ALS;Cronin;Eur. J. Hum. Genet.,2009

4. Time- and sex-dependent efficacy of magnesium sulfate to prevent behavioral impairments and cerebral damage in a mouse model of cerebral palsy;Daher;Neurobiol. Dis.,2018

5. Purification and properties of the catalytic subunit of the branched-chain alpha-keto acid dehydrogenase phosphatase from bovine kidney mitochondria;Damuni;J. Biol. Chem.,1987

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