Substance P and sickle cell disease-a marker for pain and novel therapeutic approaches
Author:
Affiliation:
1. Department of Pediatrics; Division of Allergy and Immunology; Children's Hospital of Philadelphia Research Institute; Perelman School of Medicine; University of Pennsylvania; Abramson Research Center; Philadelphia PA USA
Funder
National Institutes of Health
Publisher
Wiley
Subject
Hematology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/bjh.14299/fullpdf
Reference14 articles.
1. Sickle cell pain: a critical reappraisal;Ballas;Blood,2012
2. Pharmacologic rationale for the NK1R antagonist, aprepitant, as adjunctive therapy in HIV;Barrett;Journal of Translational Medicine,2016
3. Early insights Into the neurobiology of pain in sickle cell disease: a systematic review of the literature;Brandow;Pediatric Blood Cancer,2015
4. Substance P is increased in patients with sickle cell disease and associated with hemolysis and hydroxycarbamide use;Brandow;British Journal of Hematology,2016
5. Elevated plasma substance P in sickle cell disease and vaso-occlusive crisis;Douglas;Medical Hypotheses,2008
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3. Mast Cells Induce Blood Brain Barrier Damage in SCD by Causing Endoplasmic Reticulum Stress in the Endothelium;Frontiers in Cellular Neuroscience;2019-02-19
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