Phenotypic characterization of regulatory T cells from antiretroviral-naive HIV-1-infected people

Author:

Ambada Georgia N.12,Ntsama Claudine E.2,Nji Nadesh N.1,Ngu Loveline N.13,Sake Carole N.13,Lissom Abel12,Tchouangeu Flaurent T.14,Tchadji Jules12,Sosso Martin1,Etoa François-Xavier5,Nchinda Godwin W.1ORCID

Affiliation:

1. Laboratory of Vaccinology/Biobanking; the Chantal Biya International Reference Centre for Research on the Prevention and Management of HIV/AIDS; Yaounde Cameroon

2. Department of Animal Biology and Physiology; Faculty of Sciences; University of Yaounde one; Yaounde Cameroon

3. Department of Biochemistry; Faculty of Sciences; University of Yaounde one; Yaounde Cameroon

4. Department of Biochemistry; University of Dschang; Dschang Cameroon

5. Department of Microbiology; University of Yaounde one; Yaounde Cameroon

Funder

CIRCB

European and Developing Countries Clinical Trials Partnership

TWAS

Canada Grand Challenge

African Korean Collaborative Grant

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Reference40 articles.

1. HIV-associated chronic immune activation;Paiardini;Immunol Rev,2013

2. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases;Sakaguchi;J Immunol,1995

3. The role of regulatory T cells in chronic and acute viral infections;Keynan;Clin Infect Dis,2008

4. Regulatory T cells in immunologic self-tolerance and autoimmune disease;Sakaguchi;Int Rev Immunol,2005

5. HIV infection of human regulatory T cells downregulates Foxp3 expression by increasing DNMT3b levels and DNA methylation in the FOXP3 gene;Pion;AIDS,2013

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