Tools used to measure the impact of comorbidities on surgical outcomes in children with complex chronic conditions: A scoping review

Author:

Difazio Rachel L.12ORCID,Strout Tania D.34,Dorste Anna5,Berry Jay G.26ORCID,Vessey Judith A.7

Affiliation:

1. Department of Orthopedic Surgery and Sports Medicine Boston Children's Hospital Boston MA USA

2. Harvard Medical School Harvard University Boston MA USA

3. Department of Emergency Medicine Maine Medical Center Portland ME USA

4. Tufts University School of Medicine Boston MA USA

5. Medical Library Boston Children's Hospital Boston MA USA

6. Complex Care, Division of General Pediatrics Boston Children's Hospital Boston MA USA

7. Medical, Surgical, and Behavioral Health Nursing Programs Boston Children's Hospital Boston MA USA

Abstract

AbstractAimTo identify and describe assessment tools used to measure the impact of comorbidities on postoperative outcomes in children with complex chronic conditions (CCC).MethodThis was a scoping review using five electronic databases. The search was conducted in March 2022 by a medical librarian. There were no date or language restrictions. Included studies were full‐text articles published in peer‐reviewed journals that described a tool used to measure the impact of comorbidities in children with CCC to assess postoperative outcomes. A standardized data charting tool was used.ResultsA total of 2157 articles were retrieved. Five studies reporting on six comorbidity measures met inclusion criteria. All were cohort studies and were secondary analyses of data from an administrative database (n = 4) or a patient registry (n = 1). Sample sizes ranged from 645 to 25 747 participants. One paper described the assessment of reliability. Only one form of validity – predictive validity – was assessed in three papers for five measures.InterpretationFindings from this scoping review revealed a paucity of comorbidity assessment tools validated for use with children with CCC; significant conceptual and measurement challenges exist in the current scientific literature.What this paper adds Five studies used formal risk assessment approaches to evaluate postoperative outcomes in children with complex chronic conditions. Conceptual and methodological differences between comorbidity indexes and risk prediction models are explicated. Further development of prediction science is needed for determining postoperative outcomes. Enhanced preoperative comorbidity assessment will identify children at risk of poor outcomes.

Funder

Gordon and Betty Moore Foundation

Publisher

Wiley

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