PF‐06526290 can both enhance and inhibit conduction through voltage‐gated sodium channels
Author:
Affiliation:
1. Department of Molecular and Cellular PhysiologyStanford University Stanford CA USA
2. Icagen Inc. Durham NC 27703 USA
Publisher
Wiley
Subject
Pharmacology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1111/bph.14338
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1. The scorpion toxin Amm VIII induces pain hypersensitivity through gain-of-function of TTX-sensitive Na+ channels
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3. THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Voltage-gated ion channels
4. Subtype-Selective Small Molecule Inhibitors Reveal a Fundamental Role for Nav1.7 in Nociceptor Electrogenesis, Axonal Conduction and Presynaptic Release
5. Discovery and Optimization of Selective Nav1.8 Modulator Series That Demonstrate Efficacy in Preclinical Models of Pain
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