In vitro assessments predict that CYP3A4 contributes to a greater extent than CYP3A5 to prednisolone clearance-Reference-Cited by-同舟云学术

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In vitro assessments predict that CYP3A4 contributes to a greater extent than CYP3A5 to prednisolone clearance

Published:2021-09-24 Issue:6 Volume:129 Page:427-436
ISSN:1742-7835
Container-title:Basic & Clinical Pharmacology & Toxicology
language:en
Short-container-title:Basic Clin Pharmacol Toxicol

Author:

Skauby Ragnhild Heier¹²³^ORCID,Bergan Stein¹⁴,Andersen Anders M.¹,Vethe Nils Tore¹,Christensen Hege⁴

Affiliation:

1. Department of Pharmacology Oslo University Hospital Oslo Norway

2. Department of Medical Biochemistry Oslo University Hospital Oslo Norway

3. Faculty of Medicine, Institute of Clinical Medicine University of Oslo Oslo Norway

4. Section for Pharmacology and Pharmaceutical Biosciences, Department of Pharmacy University of Oslo Oslo Norway

Publisher

Wiley

Subject

Pharmacology,Toxicology,General Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/bcpt.13645

Reference51 articles.

1. Pharmacokinetics and Pharmacodynamics of Systemically Administered Glucocorticoids

2. Detection and characterization of prednisolone metabolites in human urine by LC-MS/MS

3. Evaluation of 6β-Hydroxycortisol, 6β-Hydroxycortisone, and a Combination of the Two as Endogenous Probes for Inhibition of CYP3A4 In Vivo

4. Studies on the expression and metabolic capabilities of human liver cytochrome P450IIIA5 (HLp3);Wrighton SA;Mol Pharmacol,1990

5. Clinical Pharmacokinetics and Pharmacodynamics of Prednisolone and Prednisone in Solid Organ Transplantation

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3. Evaluation of the potential drug–drug interactions of carotegrast methyl with midazolam, prednisolone or atorvastatin in healthy adults;British Journal of Clinical Pharmacology;2023-12-19

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