Discovery of lipophilic two‐pore channel agonists-Reference-Cited by-同舟云学术

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Discovery of lipophilic two‐pore channel agonists

Published:2020-06-14 Issue:24 Volume:287 Page:5284-5293
ISSN:1742-464X
Container-title:The FEBS Journal
language:en
Short-container-title:FEBS J.

Author:

Gerndt Susanne¹,Krogsaeter Einar²,Patel Sandip³,Bracher Franz¹,Grimm Christian²^ORCID

Affiliation:

1. Department of Pharmacy – Center for Drug Research Ludwig‐Maximilians‐Universität Munich Germany

2. Walther Straub Institute of Pharmacology and Toxicology Faculty of Medicine Ludwig‐Maximilians‐Universität Munich Germany

3. Department of Cell and Developmental Biology University College London London UK

Funder

Deutsche Forschungsgemeinschaft

Biotechnology and Biological Sciences Research Council

Publisher

Wiley

Subject

Cell Biology,Molecular Biology,Biochemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/febs.15432

Reference48 articles.

1. NAADP mobilizes calcium from acidic organelles through two-pore channels

2. TPC2 Is a Novel NAADP-sensitive Ca2+ Release Channel, Operating as a Dual Sensor of Luminal pH and Ca2+

3. Characterization of Two-pore Channel 2 (TPCN2)-mediated Ca2+ Currents in Isolated Lysosomes

4. Essential requirement for two-pore channel 1 in NAADP-mediated calcium signaling

5. An NAADP-gated Two-pore Channel Targeted to the Plasma Membrane Uncouples Triggering from Amplifying Ca2+ Signals

Cited by 15 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Structural basis for inhibition of the lysosomal two-pore channel TPC2 by a small molecule antagonist;Structure;2024-08

2. Plasticity of the selectivity filter is essential for permeation in lysosomal TPC2 channels;Proceedings of the National Academy of Sciences;2024-07-29

3. Unveiling the impact of lysosomal ion channels: balancing ion signaling and disease pathogenesis;The Korean Journal of Physiology & Pharmacology;2023-07-01

4. Electrophysiology of Endolysosomal Two-Pore Channels: A Current Account;Cells;2022-08-02

5. Segregated cation flux by TPC2 biases Ca2+ signaling through lysosomes;Nature Communications;2022-08-02

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