1. Department of Pharmacology, Biosciences Institute of Botucatu São Paulo State University, UNESP Botucatu Sao Paulo Brazil
2. Department of Anesthesiology, Botucatu Medical School Sao Paulo State University, UNESP Botucatu Sao Paulo Brazil
3. Unit of Biotechnology University of Ribeirao Preto, UNAERP Ribeirao Preto Sao Paulo Brazil