Off-targets effects underlie the inhibitory effect of FAK inhibitors on platelet activation: studies using Fak -deficient mice-Reference-Cited by-同舟云学术

Off-targets effects underlie the inhibitory effect of FAK inhibitors on platelet activation: studies using Fak -deficient mice

Published:2013-09 Issue:9 Volume:11 Page:1776-1778
ISSN:1538-7933
Container-title:Journal of Thrombosis and Haemostasis
language:en
Short-container-title:J Thromb Haemost

Author:

Roh M. E.¹,Cosgrove M.¹,Gorski K.¹,Hitchcock I. S.¹

Affiliation:

1. Department of Medicine; Stony Brook University; Stony Brook NY USA

Funder

American Heart Association

Publisher

Wiley

Subject

Hematology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/jth.12343/fullpdf

Reference13 articles.

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2. Tyrosine phosphorylation of pp 125FAK in platelets requires coordinated signaling through integrin and agonist receptors;Shattil;J Biol Chem,1994

3. Tyrosine phosphorylation and cytoskeletal reorganization in platelets are triggered by interaction of integrin receptors with their immobilized ligands;Haimovich;J Biol Chem,1993

4. Roles of focal adhesion kinase (FAK) in megakaryopoiesis and platelet function: studies using a megakaryocyte lineage specific FAK knockout;Hitchcock;Blood,2008

5. Pf4-Cre transgenic mice allow the generation of lineage-restricted gene knockouts for studying megakaryocyte and platelet function in vivo;Tiedt;Blood,2007

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