Role of pelvic drain and timing of urethral catheter removal following RARP: a systematic review and meta‐analysis

Author:

Yanagisawa Takafumi12ORCID,Kawada Tatsushi13ORCID,Mostafaei Hadi14ORCID,Sari Motlagh Reza15ORCID,Quhal Fahad16,Laukhtina Ekaterina1ORCID,Rajwa Pawel17ORCID,von Deimling Markus18,Bianchi Alberto19,Pallauf Maximilian110ORCID,Pradere Benjamin111,Karakiewicz Pierre I.12,Miki Jun2ORCID,Kimura Takahiro2,Shariat Shahrokh F.113141516

Affiliation:

1. Department of Urology, Comprehensive Cancer Center Medical University of Vienna Vienna Austria

2. Department of Urology The Jikei University School of Medicine Tokyo Japan

3. Department of Urology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Okayama University Okayama Japan

4. Research Center for Evidence Based Medicine Tabriz University of Medical Sciences Tabriz Iran

5. Men's Health and Reproductive Health Research Center Shahid Beheshti University of Medical Sciences Tehran Iran

6. Department of Urology King Fahad Specialist Hospital Dammam Saudi Arabia

7. Department of Urology Medical University of Silesia Zabrze Poland

8. Department of Urology University Medical Center Hamburg‐Eppendorf Hamburg Germany

9. Department of Urology, Azienda Ospedaliera Universitaria Integrata University of Verona Verona Italy

10. Department of Urology, University Hospital Salzburg Paracelsus Medical University Salzburg Salzburg Austria

11. Department of Urology La Croix Du Sud Hospital Quint Fonsegrives France

12. Cancer Prognostics and Health Outcomes Unit, Division of Urology University of Montreal Health Center Montreal QC Canada

13. Karl Landsteiner Institute of Urology and Andrology Vienna Austria

14. Hourani Center for Applied Scientific Research Al‐Ahliyya Amman University Amman Jordan

15. Department of Urology University of Texas Southwestern Medical Center Dallas TX USA

16. Department of Urology Weill Cornell Medical College New York NY USA

Abstract

ObjectivesTo assess the clinical value of routine pelvic drain (PD) placement and early removal of urethral catheter (UC) in patients undergoing robot‐assisted radical prostatectomy (RARP), as perioperative management such as the necessity of PD or optimal timing for UC removal remains highly variable.MethodsMultiple databases were searched for articles published before March 2022 according to the Preferred Reporting Items for Systematic Review and Meta‐Analyses (PRISMA) statement. Studies were deemed eligible if they investigated the differential rate of postoperative complications between patients with/without routine PD placement and with/without early UC removal, defined as UC removal at 2–4 days after RARP.ResultsOverall, eight studies comprising 5112 patients were eligible for the analysis of PD placement, and six studies comprising 2598 patients were eligible for the analysis of UC removal. There were no differences in the rate of any complications (pooled odds ratio [OR] 0.89, 95% confidence interval [CI] 0.78–1.00), severe complications (Clavien–Dindo Grade ≥III; pooled OR 0.95, 95% CI 0.54–1.69), all and/or symptomatic lymphocele (pooled OR 0.82, 95% CI 0.50–1.33; and pooled OR 0.58, 95% CI 0.26–1.29, respectively) between patients with or without routine PD placement. Furthermore, avoiding PD placement decreased the rate of postoperative ileus (pooled OR 0.70, 95% CI 0.51–0.91). Early removal of UC resulted in an increased likelihood of urinary retention (OR 6.21, 95% CI 3.54–10.9) in retrospective, but not in prospective studies. There were no differences in anastomosis leakage and early continence rates between patients with or those without early removal of UC.ConclusionsThere is no benefit for routine PD placement after standard RARP in the published articles. Early removal of UC seems possible with the caveat of the increased risk of urinary retention, while the effect on medium‐term continence is still unclear. These data may help guide the standardisation of postoperative procedures by avoiding unnecessary interventions, thereby reducing potential complications and associated costs.

Publisher

Wiley

Subject

Urology

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