Does the addition of perineal block enhance pain control after a haemorrhoidectomy? A prospective randomized, double‐blind placebo‐controlled study

Author:

Markaryan Daniil1,Garmanova Tatiana1,Kazachenko Ekaterina1ORCID,Lukianov Alexander1,Markaryan Eduard2,Agapov Mikhail3

Affiliation:

1. Surgical Department Medical Research Educational Centre, Lomonosov Moscow State University Moscow Russian Federation

2. Department of Coloproctology Clinic of Colorectal and Minimally Invasive Surgery of the Sechenov University Hospital №2 Moscow Russian Federation

3. Department of Surgical Disciplines Immanuel Kant Baltic Federal University, the Head of the Scientific and Educational "Institute of Medicine and Life Sciences (Medbio)" Kaliningrad Russian Federation

Abstract

AbstractBackgroundHaemorrhoidectomy is associated with severe postoperative pain, a long rehabilitation, and QoL worsening for months. Most patients experience mild‐to‐moderate postoperative pain. We aimed to evaluate the intraoperative perineal block role for patients undergoing haemorrhoidectomy.MethodsIn this prospective randomized, double‐blind, placebo‐controlled study, eligible patients with III–IV stage haemorrhoids were randomized to the experimental group (EG) with intraoperative perineal block and spinal anaesthesia and the control one (CG) only with spinal anaesthesia. During the postoperative period, the opioid consumption rate was evaluated as a primary endpoint, and the postoperative pain level according to VAS, systemic analgesics consumption, readmission, and complication rate, the timing of returning to work, patients' QoL, and overall satisfaction according to SF‐36 were evaluated as secondary endpoints.ResultsOne hundred patients completed the study (48 in EG and 52 in CG). Patients of the EG had less postoperative pain intensity (P < 0.0001), required less opioid analgesia (P = 0.03), and had longer pain‐free postoperative periods (P = 0.0002). 90% of patients in the CG required additional NSAID injections for adequate analgesia compared with only 58% in the EG. The average hospital stays, complication rate, and average operation duration didn't reach clinical significance. General health evaluation according to the SF‐36 score and the median satisfaction rate was better in the EG (P < 0.001 and P = 0.012, respectively).ConclusionsThe administration of the perianal block is safe and effective and should be administered to appropriate patients undergoing anorectal surgery.

Publisher

Wiley

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