Viral infections in critical care: a narrative review

Author:

Conway Morris A.12ORCID,Smielewska A.34ORCID

Affiliation:

1. Division of Anaesthesia, Department of Medicine University of Cambridge UK

2. John V Farman Intensive Care Unit Addenbrooke's Hospital Cambridge UK

3. Department of Clinical Virology, LCL, CSSB Liverpool University Hospitals NHS Foundation Trust Liverpool UK

4. School of Clinical Medicine University of Liverpool UK

Abstract

SummaryViral infections form a substantial part of the intensive care workload, even before the recent and ongoing COVID‐19 pandemic. The growing availability of molecular diagnostics for viral infections has led to increased recognition of these pathogens. This additional information, however, provides new challenges for interpretation and management. As the SARS‐CoV‐2 pandemic has amply demonstrated, the emergence and global spread of novel viruses are likely to provide continued challenges for critical care physicians into the future. This article will provide an overview of viral infections relevant to the critical care physician, discussing the diagnosis and management of respiratory viral infections, blood borne and enteric viruses. We will also discuss herpesviridae complications, commonly seen due to reactivation of latent infections. Further, we explore some rarer and emerging viruses, including recognition of viral haemorrhagic fevers, and briefly discuss post‐viral syndromes which may present to the intensive care unit. Finally, we will discuss infection control and its importance in preventing nosocomial viral transmission.

Funder

Medical Research Council Canada

Publisher

Wiley

Subject

Anesthesiology and Pain Medicine

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