It's time to phase out “serologic weak D phenotype” and resolve D types with RHD genotyping including weak D type 4

Author:

Flegel Willy A.12ORCID,Denomme Gregory A.3ORCID,Queenan John T.4,Johnson Susan T.5,Keller Margaret A.6,Westhoff Connie M.7ORCID,Katz Louis M.8,Delaney Meghan9,Vassallo Ralph R.10,Simon Clayton D.11,Sandler S. Gerald1

Affiliation:

1. Department of Pathology and Laboratory MedicineMedStar Georgetown University Hospital Washington, DC USA

2. Department of Transfusion Medicine, NIH Clinical CenterNational Institutes of Health Bethesda Maryland USA

3. Diagnostic LaboratoriesVersiti Milwaukee Wisconsin USA

4. Department of Obstetrics and GynecologyMedStar Georgetown University Hospital Washington, DC USA

5. Clinical EducationVersiti Milwaukee Wisconsin USA

6. National Molecular LaboratoryAmerican Red Cross Biomedical Services Philadelphia Pennsylvania USA

7. Laboratory of Immunohematology and GenomicsNew York Blood Center Enterprises New York New York USA

8. Mississippi Valley Regional Blood Center Davenport Iowa USA

9. Childrenʼs National Medical Center Washington, DC USA

10. Vitalant Scottsdale Arizona USA

11. Defense Health AgencyArmed Services Blood Program Office Falls Church Virginia USA

Funder

NIH Clinical Center

Publisher

Wiley

Subject

Hematology,Immunology,Immunology and Allergy

Reference51 articles.

1. AABB Statements. Joint statement on phasing‐in RHD genotyping for pregnant women and other females of childbearing potential with a serologic weak D phenotype. 2015 [cited 2019 May 5]. Available from:http://www.aabb.org/advocacy/statements/Pages/statement150722.aspx.

2. It's time to phase inRHDgenotyping for patients with a serologic weak D phenotype

3. A proposal to standardize terminology for weak D antigen

4. Significantly enhanced testing sensitivities of automated ORTHO VISION analyzers detect weak D phenotypes

5. Red cell genotyping precision medicine: a conference summary

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