AKT in cancer: new molecular insights and advances in drug development

Author:

Mundi Prabhjot S.12,Sachdev Jasgit3,McCourt Carolyn4,Kalinsky Kevin12

Affiliation:

1. Division of Medical Oncology, College of Physicians and Surgeons; Columbia University Medical Center; New York NY USA

2. Herbert Irving Comprehensive Cancer Center; Columbia University; New York NY USA

3. Translational Genomics Research Institute; Virginia G. Piper Cancer Center at HonorHealth; Scottsdale AZ USA

4. Division of Gynecologic Oncology; Washington University School of Medicine in St Louis; St Louis MO USA

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference101 articles.

1. The phosphatidylinositol 3-kinase-AKT pathway in human cancer;Vivanco;Nat Rev Cancer,2002

2. PI3K/AKT signaling pathway and cancer;Vara;Cancer Treat Rev,2004

3. Guide to receptors and channels (GRAC), 5th edition;Alexander;Br J Pharmacol,2011

4. Targeting the AKT protein kinase for cancer chemoprevention;Crowell;Mol Cancer Ther,2007

5. The PTEN/PI3K/AKT pathway in vivo, cancer mouse models;Camero;Front Oncol,2014

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