Associations of the CYP3A5*3 and CYP3A4 *1G polymorphisms with the pharmacokinetics of oral midazolam and the urinary 6β-hydroxycortisol/cortisol ratio as markers of CYP3A activity in healthy male Chinese
Author:
Affiliation:
1. Department of Medicine and Therapeutics; Prince of Wales Hospital; The Chinese University of Hong Kong; NT Hong Kong SAR China
2. School of Pharmacy; The Chinese University of Hong Kong; Hong Kong SAR China
Funder
Research Grants Council, University Grants Committee
Publisher
Wiley
Subject
Pharmacology (medical),Pharmacology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/jcpt.12433/fullpdf
Reference38 articles.
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2. Influence of CYP3A5 genotype on the pharmacokinetics and pharmacodynamics of the cytochrome P4503A probes alfentanil and midazolam;Kharasch;Clin Pharmacol Ther,2007
3. Pharmacogenomics of cytochrome P450 3A4: recent progress toward the “missing heritability” problem;Klein;Front Genet,2013
4. Cytochrome P450 enzymes in drug metabolism: regulation of gene expression, enzyme activities, and impact of genetic variation;Zanger;Pharmacol Ther,2013
5. Significance of the minor cytochrome P450 3A isoforms;Daly;Clin Pharmacokinet,2006
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