1. Departments of Anaesthesia and Physiology; St. Michael's Hospital; University of Toronto; Toronto; ON; Canada
2. Division of Cardiology; Department of Medicine; St. Michael's Hospital; University of Toronto; Toronto; ON; Canada
3. Keenan Research Centre of the Li Ka Shing Knowledge Institute; St. Michael's Hospital; University of Toronto; Toronto; ON; Canada
4. Department of Pharmacology; University of Toronto; Toronto; ON; Canada
5. Department of Biochemistry and Biophysics; University of Pennsylvania; Philadelphia; PA; USA
6. Institute of Medical Science; University of Toronto; Toronto; ON; Canada