Affiliation:
1. Phoenix Children's Hospital and the University of Arizona College of Medicine Tucson Arizona USA
2. Mattel Children's Hospital and the University of California at Los Angeles Los Angeles California USA
Abstract
AbstractBackgroundRecurrent disease after kidney transplant remains an important cause of allograft failure, accounting for 7‐8% of graft loss and ranking as the fifth most common cause of allograft loss in the pediatric population. Although the pathophysiology of many recurrent diseases is incompletely understood, recent advances in basic science and therapeutics are improving outcomes and changing the course of several of these conditions.MethodsReview of the literature.ResultsWe discuss the diagnosis and management of recurrent disease.ConclusionWe highlight new insights into the pathophysiology and treatment of post‐transplant primary hyperoxaluria, focal segmental glomerulosclerosis, immune complex glomerulonephritis, C3 glomerulopathy, lupus nephritis, atypical hemolytic uremic syndrome, and IgA nephropathy.