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Elevated cerebrospinal fluid neurofilament light levels in patients with amyotrophic lateral sclerosis: a possible marker of disease severity and progression

  • Published:2012-06-11 Issue:12 Volume:19 Page:1561-1567
  • ISSN:1351-5101
  • Container-title:European Journal of Neurology
  • language:en
  • Short-container-title:Eur J Neurol

Author:

Tortelli R.1,Ruggieri M.1,Cortese R.1,D'Errico E.1,Capozzo R.1,Leo A.1,Mastrapasqua M.1,Zoccolella S.1,Leante R.1,Livrea P.1,Logroscino G.1,Simone I. L.1

Affiliation:

1. Department of Neurosciences and Sense Organs; University of Bari; Policlinico Bari Italy

Funder

Italian Ministry of Health

Publisher

Wiley

Subject

Neurology (clinical),Neurology

Reference36 articles.

1. Amyotrophic lateral sclerosis - looking for pathogenesis and effective therapy;Naganska;Folia Neuropathol,2011

2. Axonal damage markers in cerebrospinal fluid are increased in ALS;Brettschneider;Neurology,2006

3. Defective axonal transport in a transgenic mouse model of amyotrophic lateral sclerosis;Collard;Nature,1995

4. Accumulation of phosphorylated neurofilaments in anterior horn motoneurons of amyotrophic lateral sclerosis patients;Munoz;J Neuropathol Exp Neurol,1988

5. Neurofilaments in health and disease;Julien;Prog Nucleic Acid Res Mol Biol,1998
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