A multicentre, phase II trial of ofatumumab monotherapy in relapsed/progressive diffuse large B-cell lymphoma

Author:

Coiffier Bertrand1,Radford John2,Bosly André3,Martinelli Giovanni4,Barca Gabriela5,Davies Andrew6,Decaudin Didier7,Gallop-Evans Eve8,Padmanabhan-Iyer Swaminathan9,Van Eygen Koen10,Wu Ka Lung11,Gupta Ira V.12,Lin Thomas S.12,Goldstein Nancy13,Jewell Roxanne C.13,Winter Paul14,Lisby Steen15,

Affiliation:

1. Service d'Hematologie; Hospices Civils de Lyon; Lyon; France

2. The Christie NHS Foundation Trust and The University of Manchester; Manchester; UK

3. Service d'Hématologie; Clinique Universitaires UCL de Mont-Godinne; Yvoir; Belgium

4. Divisione di Ematoncologia; Istituto Europeo di Oncologia; Milan; Italy

5. Department of Hematology; Coltea Clinical Hospital; Bucharest; Romania

6. Cancer Research UK Centre; University of Southampton; Southampton; UK

7. Departments of Medical Oncology and Translational Research; Institut Curie; Paris; France

8. Department of Clinical Oncology; Velindre Cancer Centre; Cardiff; UK

9. Institute for Drug Development; University of Texas Health Science Center at San Antonio; San Antonio; TX; USA

10. Oncologisch Centrum; AZ Groeninge; Kortrijk; Belgium

11. Department of Hematology; Ziekenhuis Stuivenberg; Antwerpen; Belgium

12. GlaxoSmithKline; Collegeville; PA; USA

13. GlaxoSmithKline; Research Triangle Park; NC; USA

14. GlaxoSmithKline; London; UK

15. Genmab; Copenhagen; Denmark

Publisher

Wiley

Subject

Hematology

Reference18 articles.

1. How I treat patients with diffuse large B-cell lymphoma;Armitage;Blood,2007

2. Revised response criteria for malignant lymphoma;Cheson;Journal of Clinical Oncology,2007

3. Chemotherapy-Refractory Diffuse Large B-Cell Lymphomas (DLBCL) are effectively killed by Ofatumumab-induced complement-mediated cytoxicity;Cillessen;Blood (ASH Annual Meeting Abstracts),2007

4. Rituximab (anti-CD20 monoclonal antibody) for the treatment of patients with relapsing or refractory aggressive lymphoma: a multicenter phase II study;Coiffier;Blood,1998

5. CHOP chemotherapy plus rituximab compared with CHOP alone in elderly patients with diffuse large-B-cell lymphoma;Coiffier;New England Journal of Medicine,2002

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