1. Department of Pharmacology, Fukui Medical University, 23 Shimoaizuki, Matsuoka, Fukui 910‐1193, Japan
2. Department of Molecular Design, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, 2‐3‐10 Surugadai, Kanda, Chiyoda‐ku, Tokyo 101‐0062, Japan
3. Department of Pathology, School of Medicine, Fukui Medical University, 23 Shimoaizuki, Matsuoka, Fukui 910‐1193, Japan
4. Department of Pharmacology and Therapeutics and Department of Medicine, Faculty of Medicine, The University of Calgary, 3330 Hospital Drive NW, Calgary, Alberta, Canada T2N 4N1