1. Department of Anatomy and Developmental Biology, the Royal Free and University College Medical School, University of London, Rowland Hill Street, London NW3 2PF, UK,
2. Department of Physiology and Biophysics, University of Illinois Medical Center, Chicago, IL 60680, USA, and UK
3. The Surgical Unit, Saint Bartholomews and the Royal London School of Medicine and Dentistry, University of London, Turner Street, London E1 2AD, UK