Inhaled dry powder apomorphine (VR040) for ‘off ’ periods in Parkinson's disease: an in-clinic double-blind dose ranging study
Author:
Affiliation:
1. Department of Neurology; Institute of Neurological Sciences; Southern General Hospital; Glasgow; UK
2. Vectura Group plc; Chippenham; Wiltshire; UK
Publisher
Wiley
Subject
Clinical Neurology,Neurology,General Medicine
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/ane.12107/fullpdf
Reference15 articles.
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2. A double-blind, placebo-controlled study of intranasal apomorphine spray as a rescue agent for off-states in Parkinson's disease;Dewey;Mov Disord,1998
3. Pharmacokinetic-pharmacodynamic relationships of apomorphine in patients with Parkinson's disease;Neef;Clin Pharmacokinet,1999
4. Grosset K Morgan F Grosset D Phase IIa randomized double-blind, placebo-controlled, study of inhaled apomorphine in patients with established Parkinson's disease Kyoto, Japan
5. Stimulation of both D1 and D2 dopamine receptors appears necessary for full expression of postsynaptic effects of dopamine agonists: a neurophysiological study;Carlson;Brain Res,1987
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