Evidence of the immunomodulatory role of dual PI3K/mTOR inhibitors in transplantation: an experimental study in mice

Author:

Vilchez Valery1,Turcios Lilia1,Butterfield David A.23,Mitov Mihail I.2,Coquillard Cristin L.1,Brandon Ja Anthony4,Cornea Virgilius5,Gedaly Roberto1ORCID,Marti Francesc1

Affiliation:

1. Department of Surgery; College of Medicine; University of Kentucky; Lexington KY USA

2. Redox Metabolism (RM) Shared Resource Facility (SRF); Markey Cancer Center; College of Medicine; University of Kentucky; Lexington KY USA

3. Department of Chemistry; College of Medicine; University of Kentucky; Lexington KY USA

4. Department of Internal Medicine; College of Medicine; University of Kentucky; Lexington KY USA

5. Department of Pathology and Laboratory Medicine; College of Medicine; University of Kentucky; Lexington KY USA

Funder

National Cancer Institute

Publisher

Frontiers Media SA

Subject

Transplantation

Reference75 articles.

1. Tolerance in organ transplantation: from conventional immunosuppression to extracellular vesicles;Monguió-Tortajada;Front Immunol,2014

2. Acute and Chronic Allograft Dysfunction in Kidney Transplant Recipients;Goldberg;Med Clin North Am,2016

3. Current views on chronic rejection after lung transplantation;Verleden;Transpl Int,2015

4. Alloantigen specific T regulatory cells in transplant tolerance;Hall;Int Immunopharmacol,2009

5. Regulatory T cells and transplantation tolerance;Hilbrands;Immunotherapy,2013

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