The efficacy of natural products for the treatment of nasopharyngeal carcinoma

Author:

Ao Xudong1,Luo Chao2,Zhang Mengni1,Liu Lisha1,Peng Shunlin1

Affiliation:

1. Department of Otolaryngology Hospital of Chengdu University of Traditional Chinese Medicine Chengdu China

2. Medical Department Hospital of Chengdu University of Traditional Chinese Medicine Chengdu China

Abstract

AbstractNasopharyngeal carcinoma (NPC) is a malignant tumor originating in the nasopharyngeal epithelium with a high incidence in southern China and parts of Southeast Asia. The current treatment methods are mainly radiotherapy and chemotherapy. However, they often have side effects and are not suitable for long‐term exposure. Natural products have received more and more attention in cancer prevention and treatment because of their its high efficiency, low toxic side effects, and low toxicity. Natural products can serve as a viable alternative, and this study aimed to review the efficacy and mechanisms of natural products in the treatment of NPC by examining previous literature. Most natural products act by inhibiting cell proliferation, metastasis, inducing cell cycle arrest, and apoptosis. Although further research is needed to verify their effectiveness and safety, natural products can significantly improve the treatment of NPC.

Publisher

Wiley

Subject

Molecular Medicine,Biochemistry,Drug Discovery,Pharmacology,Organic Chemistry

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