Design, synthesis, and molecular modeling of coumarin derivatives as MDM2 inhibitors targeting breast cancer-Reference-Cited by-同舟云学术

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Design, synthesis, and molecular modeling of coumarin derivatives as MDM2 inhibitors targeting breast cancer

Published:2022-02-22 Issue:4 Volume:99 Page:609-619
ISSN:1747-0277
Container-title:Chemical Biology & Drug Design
language:en
Short-container-title:Chem Biol Drug Des

Author:

Ahmed Eman Y.¹,Abdel Latif Nehad A.¹,Nasr Tamer²^ORCID,Awad Hanem M.³,Abdelhafez Omaima M.¹

Affiliation:

1. Chemistry of Natural Compounds Department Pharmaceutical and Drug Industries Research Institute National Research Centre Dokki Egypt

2. Department of Pharmaceutical Chemistry Faculty of Pharmacy Helwan University Helwan Egypt

3. Tanning Materials and Leather Technology Department National Research Centre Dokki Egypt

Publisher

Wiley

Subject

Molecular Medicine,Biochemistry,Drug Discovery,Pharmacology,Organic Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/cbdd.14028

Reference21 articles.

1. Design and molecular modeling of novel P38α MAPK inhibitors targeting breast cancer, synthesized from oxygen heterocyclic natural compounds

2. VEGFR-2 inhibiting effect and molecular modeling of newly synthesized coumarin derivatives as anti-breast cancer agents

3. Angiokinase inhibition of VEGFR-2, PDGFR and FGFR and cell growth inhibition in lung cancer: Design, synthesis, biological evaluation and molecular docking of novel azaheterocyclic coumarin derivatives

4. Synthesis and Cytotoxic Activity of New 1,3,4-Thiadiazole Thioglycosides and 1,2,3-Triazolyl-1,3,4-Thiadiazole N-glycosides

5. Coumarin-chalcone hybrid instigates DNA damage by minor groove binding and stabilizes p53 through post translational modifications

Cited by 5 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Anticancer activity of new triazolopyrimidine linked coumarin and quinolone hybrids: Synthesis, molecular modeling, TrkA, PI3K/AKT and EGFR inhibition;Journal of Molecular Structure;2024-06

2. Insight on Heterocycles as p53‐MDM2 Protein‐Protein Interaction Inhibitors: Molecular Mechanism for p53 Activation;ChemistrySelect;2024-03-06

3. Naturally based pyrazoline derivatives as aminopeptidase N, VEGFR2 and MMP9 inhibitors: design, synthesis and molecular modeling;RSC Advances;2024

4. Synthesis and crystal structures of (E)-N′-(4-chloro-3-nitrobenzylidene)acetohydrazide and (E)-2-(4-chlorobenzylidene)-1-(quinolin-8-yl)hydrazine;Acta Crystallographica Section E Crystallographic Communications;2023-07-28

5. Design of Novel Coumarin Derivatives as NUDT5 Antagonists That Act by Restricting ATP Synthesis in Breast Cancer Cells;Molecules;2022-12-22

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