Understanding the gaps in headache and migraine treatment with psychological and behavioral interventions: A narrative review

Author:

Zamir Orit123ORCID,Yarns Brandon C.45ORCID,Lagman‐Bartolome Ana Marissa167ORCID,Jobanputra Lina1,Lawler Valerie1,Lay Christine1

Affiliation:

1. Centre for Headache, Women's College Hospital University of Toronto Toronto Ontario Canada

2. Wasser Pain Medicine Clinic, Mount Sinai Hospital University of Toronto Toronto Ontario Canada

3. Department of Psychiatry Women’s College Hospital and University of Toronto Toronto Ontario Canada

4. Department of Mental Health VA Greater Los Angeles Healthcare System Los Angeles California USA

5. Department of Psychiatry and Biobehavioral Sciences David Geffen School of Medicine at UCLA Los Angeles California USA

6. Division of Neurology, Hospital for Sick Children University of Toronto Toronto Ontario Canada

7. Department of Pediatrics, Division of Neurology, Children's Hospital, London Health Sciences Center University of Western Ontario London Ontario Canada

Abstract

AbstractObjectiveIn this narrative review, we summarize relevant literature pertaining to psychosocial risk factors for headache and migraine progression, current behavioral and psychological treatments, and consider promising treatments.BackgroundHeadache and migraine are common and associated with significant burden and disability. Current treatments targeting psychosocial risk factors show modest outcomes and do not directly address the impact of early life adversity, including the development of maladaptive emotional processing. An intervention that could address these factors and include components of current evidence‐based interventions may lead to improved outcomes.MethodsWe searched PubMed and Google Scholar for articles through December 2022. Search terms included headache, migraine, psychological interventions, behavioral interventions, cognitive–behavioral therapy, mindfulness, psychiatric comorbidities, adverse childhood experiences, trauma, and emotional processing.ResultsTrauma and childhood adversity show a correlation with headache and migraine progression. Developmental adversity and trauma interfere with adaptive emotional processing, which may worsen headache and migraine symptoms, while adaptive ways of experiencing emotions are shown to improve symptoms. Current behavioral and psychological interventions, such as cognitive–behavioral and mindfulness therapies, are effective treatments for headache, but they produce small to medium effect sizes and do not directly address the impact of trauma and emotional conflicts—common factors that contribute to chronicity and disability, especially among certain subpopulations of headache patients such as those with migraine. Thus, there exists a gap in current treatment.ConclusionThere is a gap in headache and migraine treatment for those patients who have a history of trauma, childhood adversity, and maladaptive emotional processing. We suggest that an integrated psychological treatment that includes components of current evidence‐based interventions and addresses gaps by focusing on processing trauma‐related emotions may improve chronic and debilitating symptoms.

Funder

U.S. Department of Veterans Affairs

Publisher

Wiley

Subject

Neurology (clinical),Neurology

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