Therapeutic targets in myeloma bone disease
Author:
Affiliation:
1. Department of Medicine, Division Hematology/Oncology Indiana University School of Medicine Indianapolis Indiana USA
2. Roudebush VA Medical Center Indianapolis Indiana USA
Funder
Multiple Myeloma Research Foundation
Foundation for the National Institutes of Health
Publisher
Wiley
Subject
Pharmacology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1111/bph.14889
Reference152 articles.
1. Mechanism of Action of Bortezomib and the New Proteasome Inhibitors on Myeloma Cells and the Bone Microenvironment: Impact on Myeloma-Induced Alterations of Bone Remodeling
2. Osteoblast suppression in multiple myeloma bone disease
3. EZH2 or HDAC1 Inhibition Reverses Multiple Myeloma–Induced Epigenetic Suppression of Osteoblast Differentiation
4. XRK3F2 Inhibition of p62-ZZ Domain Signaling Rescues Myeloma-Induced GFI1-Driven Epigenetic Repression of the Runx2 Gene in Pre-osteoblasts to Overcome Differentiation Suppression
5. Development of Novel Immunotherapies for Multiple Myeloma
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1. The bone ecosystem facilitates multiple myeloma relapse and the evolution of heterogeneous drug resistant disease;Nature Communications;2024-03-19
2. BCMA- and CST6-specific CAR T cells lyse multiple myeloma cells and suppress murine osteolytic lesions;Journal of Clinical Investigation;2024-01-02
3. Specific binding of plant-expressed anti-PD-L1 monoclonal antibody to multiple myeloma cell line RPMI8226;Plant Biotechnology Reports;2023-11-30
4. Pharmacologic targeting of the p62 ZZ domain enhances both anti-tumor and bone-anabolic effects of bortezomib in multiple myeloma;Haematologica;2023-11-16
5. The checkpoint inhibitor PD-1H/VISTA controls osteoclast-mediated multiple myeloma bone disease;Nature Communications;2023-07-17
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