Current status of neonatal jaundice management in Japan

Author:

Honbe Kazuya12,Hayakawa Masahiro2ORCID,Morioka Ichiro3ORCID,Arai Hiroshi4,Maruo Yoshihiro5,Kusaka Takashi6,Kunikata Tetsuya7,Iwatani Sota8ORCID,Okumura Akihisa9ORCID

Affiliation:

1. Department of Pediatrics Tosei General Hospital Seto Japan

2. Division of Neonatology, Center for Maternal‐Neonatal Care Nagoya University Hospital Nagoya Japan

3. Department of Pediatrics and Child Health Nihon University School of Medicine Tokyo Japan

4. Department of Pediatric Neurology Bobath Memorial Hospital Osaka Japan

5. Department of Pediatrics Shiga University of Medical Science Otsu Japan

6. Department of Pediatrics Kagawa University School of Medicine Miki‐cho, Kita‐gun Japan

7. Department of Pediatrics, Division of Neonatal Medicine Saitama Medical University Hospital Moroyama‐machi, Iruma‐gun Japan

8. Department of Neonatology Kobe Children's Hospital Kobe Japan

9. Department of Pediatrics Aichi Medical University Nagakute Japan

Abstract

AbstractBackgroundThis nationwide survey aimed to determine the status of jaundice management in Japan.MethodsA questionnaire about bilirubin level measurements and neonatal jaundice treatment was sent to 330 institutions providing neonatal care. The responses were analyzed according to institution level.ResultsOf 330 institutions, 172 responded (52.1% response rate). Total bilirubin levels were measured in the central laboratory using spectrophotometry at 134 institutions and a blood gas analyzer at 81 institutions. Unbound bilirubin (UB) levels were measured by 79 institutions, while transcutaneous bilirubin measurements were taken at 63 institutions. There was no association between institution level and UB or transcutaneous bilirubin measurement. For phototherapy criteria, the Murata‐Imura criteria were adopted by 67 institutions, Nakamura criteria by 36, and Morioka criteria by 39. Light‐emitting diodes (LED) were used by 160 institutions versus fluorescent lights by 31. When a blue LED was used, 119 institutions used the high mode. There is no standard for increasing light intensity. No association was found between institution level and phototherapy criteria. UB was measured in 14 of 63 institutions using the Murata‐Imura criteria.ConclusionsThere is a large variation in the management and treatment of neonatal jaundice among institutes in Japan.

Publisher

Wiley

Subject

Pediatrics, Perinatology and Child Health

Reference30 articles.

1. Neonatal Hyperbilirubinemia

2. AraiH IwataniS OkadaH OkabayashiA OkumuraA KitaiM et al.The Clinical Guideline for bilirubin encephalopathy in preterm infants.2020(Japanese).

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4. Trends in Hospitalizations for Neonatal Jaundice and Kernicterus in the United States, 1988–2005

5. Movement disorders due to bilirubin toxicity

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