Cholesterol‐containing lipid nanodiscs promote an α‐synuclein binding mode that accelerates oligomerization-Reference-Cited by-同舟云学术

Cholesterol‐containing lipid nanodiscs promote an α‐synuclein binding mode that accelerates oligomerization

Published:2020-09-26 Issue:6 Volume:288 Page:1887-1905
ISSN:1742-464X
Container-title:The FEBS Journal
language:en
Short-container-title:FEBS J.

Author:

Jakubec Martin¹²^ORCID,Bariås Espen¹²,Furse Samuel²^ORCID,Govasli Morten L.¹²³^ORCID,George Vinnit⁴,Turcu Diana¹²,Iashchishyn Igor A.⁵^ORCID,Morozova‐Roche Ludmilla A.⁵^ORCID,Halskau Øyvind¹²^ORCID

Affiliation:

1. Department of Biological Sciences University of Bergen Norway

2. Department of Molecular Biology University of Bergen Norway

3. Division of Infection and Immunity University College London London UK

4. Department of Chemistry University of Bergen Norway

5. Department of Medical Biochemistry and Biophysics Umeå University Sweden

Funder

Norges Forskningsråd

Bergens Forskningsstiftelse

Vetenskapsrådet

Publisher

Wiley

Subject

Cell Biology,Molecular Biology,Biochemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/febs.15551

Reference99 articles.

1. In vivo demonstration that -synuclein oligomers are toxic

2. α-Synuclein promotes dilation of the exocytotic fusion pore

3. The Role of Lipids Interacting with α-Synuclein in the Pathogenesis of Parkinson’s Disease

4. Structural insights from lipid-bilayer nanodiscs link α-Synuclein membrane-binding modes to amyloid fibril formation

5. α-Synuclein Membrane Interactions and Lipid Specificity

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