Overproduction of 2-ketoisovalerate and monensin production by regulatory mutants ofStreptomyces cinnamonensisresistant to 2-ketobutyrate and amino acids

Author:

Pospı́šil S,Kopecký J,Přikrylová V,Spı́žek J

Publisher

Oxford University Press (OUP)

Subject

Genetics,Molecular Biology,Microbiology

Reference16 articles.

1. Biosynthesis of monensin;Day;Antimicrob. Agents Chemother.,1973

2. 2 Pospı́šil, S., Sedmera, P., Havránek, M., Krumphanzl, V. and Vaněk, Z. (1983) Biosynthesis of monensins A and B. J. Antibiot. 36, 617–619.

3. 3 Pospı́šil, S., Sedmera, P., Krumphanzl, V. and Vaněk, Z. (1986) Biosynthesis of monensins A and B: the role of isoleucine. Folia Microbiol. 31, 8–14.

4. 4 Pospı́šil, S., Peterková M., Krumphanzl, V. and Vaněk, Z. (1984) Regulatory mutants of Streptomyces cinnamonensis producing monensin A. FEMS Microbiol. Lett. 24, 209–213.

5. 5 Pospı́šil, S., Kopecký, J. and Přikrylová, V. (1998) Derepression and altered feedback regulation of valine biosynthetic pathway in analogue-resistant mutants of Streptomyces cinnamonensis resulting in 2-ketoisovalerate excretion. J. Appl. Microbiol. 85, 9–16.

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