Elevated miR‐124‐3p in the aging colon disrupts mucus barrier and increases susceptibility to colitis by targeting T‐synthase-Reference-Cited by-同舟云学术

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Elevated miR‐124‐3p in the aging colon disrupts mucus barrier and increases susceptibility to colitis by targeting T‐synthase

Published:2020-10-11 Issue:11 Volume:19 Page:
ISSN:1474-9718
Container-title:Aging Cell
language:en
Short-container-title:Aging Cell

Author:

Huang Li¹,Sun Ting‐yi¹²³^ORCID,Hu Liang‐jun¹,Hu Shi‐long¹,Sun Hai‐mei¹²³,Zhao Fu‐qian¹,Wu Bo¹²³,Yang Shu¹²³,Ji Feng‐qing¹²³,Zhou De‐shan¹²³

Affiliation:

1. Department of Histology and Embryology, School of Basic Medical Sciences Capital Medical University Beijing China

2. Beijing Key Laboratory of Cancer Invasion and Metastasis Research Beijing China

3. Cancer Institute of Capital Medical University Beijing China

Funder

Beijing Municipal Natural Science Foundation

Publisher

Wiley

Subject

Cell Biology,Ageing

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/acel.13252

Reference41 articles.

1. Metformin reduces aging‐related leaky gut and improves cognitive function by beneficially modulating gut microbiome/goblet cell/mucin axis;Ahmadi S.;The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences,2020

2. Changing global epidemiology of inflammatory bowel diseases: sustaining health care delivery into the 21st century;Ashwin N. A.;Clinical Gastroenterology and Hepatology,2020

4. Core 1– and 3–derived O-glycans collectively maintain the colonic mucus barrier and protect against spontaneous colitis in mice

5. Defective Intestinal Mucin-Type O-Glycosylation Causes Spontaneous Colitis-Associated Cancer in Mice

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