Sustained effectiveness, safety and therapeutic drug monitoring of tioguanine in a cohort of 274 IBD patients intolerant for conventional therapies

Author:

Simsek Melek1ORCID,Deben Debbie S.2,Horjus Carmen S.3,Bénard Melanie V.4,Lissenberg-Witte Birgit I.5,Buiter Hans J. C.6,van Luin Matthijs7,Seinen Margien L.4,Mulder Chris J. J.4,Wong Dennis R.2ORCID,de Boer Nanne K. H.1,van Bodegraven Adriaan A.48ORCID

Affiliation:

1. Department of Gastroenterology and Hepatology; Amsterdam UMC, Vrije Universiteit Amsterdam, AG&M Research Institute; Amsterdam The Netherlands

2. Department of Clinical Pharmacy, Clinical Pharmacology and Toxicology, Zuyderland Medical Centre; Sittard-Geleen-Heerlen; The Netherlands

3. Department of Gastroenterology and Hepatology; Rijnstate Hospital; Arnhem The Netherlands

4. Department of Gastroenterology and Hepatology; Amsterdam UMC, Vrije Universiteit Amsterdam; Amsterdam The Netherlands

5. Department of Epidemiology and Biostatistics; Amsterdam UMC, Vrije Universiteit Amsterdam; Amsterdam The Netherlands

6. Department of Clinical Pharmacology and Pharmacy; Amsterdam UMC, Vrije Universiteit Amsterdam; Amsterdam The Netherlands

7. Department of Clinical Pharmacology and Pharmacy; Rijnstate Hospital; Arnhem The Netherlands

8. Department of Gastroenterology, Geriatrics, Internal and Intensive Care Medicine (Co-MIK); Zuyderland Medical Centre, Sittard-Geleen-Heerlen; The Netherlands

Publisher

Wiley

Subject

Pharmacology (medical),Gastroenterology,Hepatology

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