Inhibition of In Vitro Metabolism of Opioids by Skeletal Muscle Relaxants

Author:

Moody David E.1,Fu Yueqiao1,Fang Wenfang B.1

Affiliation:

1. Center for Human Toxicology; Department of Pharmacology and Toxicology; University of Utah; Salt Lake City UT USA

Funder

U.S. Department of Justice

Publisher

Wiley

Subject

Pharmacology,Toxicology,General Medicine

Reference28 articles.

1. Increases in heroin overdose deaths - 28 States, 2010 to 2012;Rudd;MMWR Morb Mortal Wkly Rep,2014

2. The epidemic of prescription opioid abuse, the subsequent rising prevalence of heroin use, and the federal response;Kanouse;J Pain Palliat Care Pharmacother,2015

3. Opioid metabolism;Smith;Mayo Clin Proc,2009

4. Opioid therapies and cytochrome p450 interactions;Gudin;J Pain Symptom Manage,2012

5. In vitro inhibition of methadone and oxycodone cytochrome P450-dependent metabolism: reversible inhibition by H2-receptor agonists and proton-pump inhibitors;Moody;J Anal Toxicol,2013

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