Efficient production of biallelicGGTA1knockout pigsbycytoplasmic microinjection of CRISPR/Cas9 into zygotes-Reference-Cited by-同舟云学术

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Efficient production of biallelicGGTA1knockout pigsbycytoplasmic microinjection of CRISPR/Cas9 into zygotes

Published:2016-09 Issue:5 Volume:23 Page:338-346
ISSN:0908-665X
Container-title:Xenotransplantation
language:en
Short-container-title:Xenotransplantation

Author:

Petersen Bjoern¹,Frenzel Antje¹,Lucas-Hahn Andrea¹,Herrmann Doris¹,Hassel Petra¹,Klein Sabine¹,Ziegler Maren¹,Hadeler Klaus-Gerd¹,Niemann Heiner¹

Affiliation:

1. Institute of Farm Animal Genetics; Friedrich-Loeffler-Institut; Mariensee Neustadt Germany

Funder

“Rebirth” Cluster of Excellence

Publisher

Wiley

Subject

Transplantation,Immunology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/xen.12258/fullpdf

Reference41 articles.

1. Anti-pig IgM antibodies in human serum react predominantly with Gal(alpha 1-3)Gal epitopes;Sandrin;Proc Natl Acad Sci U S A,1993

2. One percent of human circulating B lymphocytes are capable of producing the natural anti-Gal antibody;Galili;Blood,1993

3. Heart transplantation in baboons using alpha1,3-galactosyltransferase gene-knockout pigs as donors: initial experience;Kuwaki;Nat Med,2005

4. Marked prolongation of porcine renal xenograft survival in baboons through the use of alpha1,3-galactosyltransferase gene-knockout donors and the cotransplantation of vascularized thymic tissue;Yamada;Nat Med,2005

5. Hearts from transgenic pigs constructed with CD59/DAF genomic clones demonstrate improved survival in primates;Chen;Xenotransplantation,1999

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