Small molecule nAS-E targeting cAMP response element binding protein (CREB) and CREB-binding protein interaction inhibits breast cancer bone metastasis

Author:

Jiang Min1,Yan Yufei1,Yang Kai1,Liu Zhuochao1,Qi Jin1,Zhou Hanbing1,Qian Niandong1,Zhou Qi1,Wang Tianqi1,Xu Xing1,Xiao Xiangshu2,Deng Lianfu1

Affiliation:

1. Shanghai Key Laboratory for Bone and Joint Diseases; Shanghai Institute of Traumatology and Orthopaedics, Shanghai Ruijin Hospital, Shanghai Jiaotong University School of Medicine; Shanghai China

2. Program in Chemical Biology, Department of Physiology and Pharmacology; Oregon Health & Science University; Portland Oregon

Funder

National natural science foundation of China

Shanghai Municipal Health Bureau

Shanghai Committee of Science and Technology, China

Guangci Distinguished Young Scholars Training Program

Publisher

Wiley

Subject

Cell Biology,Molecular Medicine

Reference50 articles.

1. Treatment considerations for the management of patients with hormone receptor-positive metastatic breast cancer;Visovsky;J Adv Pract Oncol,2014

2. The bone microenvironment in metastasis; what is special about bone?;Bussard;Cancer Metastasis Rev,2008

3. Advances in the biology of bone metastasis: how the skeleton affects tumor behavior;Sterling;Bone,2011

4. Crosstalk between cancer cells and bone microenvironment in bone metastasis;Yoneda;Biochem Biophys Res Comm,2005

5. Molecular mechanisms of osteolytic bone metastases;Guise;Cancer,2000

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