Hypothesis: Caco-2 cell rotational 3D mechanogenomic turing patterns have clinical implications to colon crypts

Author:

Zheng Gen1ORCID,Kalinin Alexandr A.23,Dinov Ivo D.234,Meixner Walter2,Zhu Shengtao56,Wiley John W.1

Affiliation:

1. Division of Gastroenterology; Department of Internal Medicine; University of Michigan Medical School; Ann Arbor Michigan

2. Department of Computational Medicine and Bioinformatics; University of Michigan Medical School; Ann Arbor Michigan

3. Statistics Online Computational Resource (SOCR); University of Michigan School of Nursing; Ann Arbor Michigan

4. Michigan Institute for Data Science (MIDAS); University of Michigan; Ann Arbor Michigan

5. Department of Digestive Diseases; Beijing Friendship Hospital; Capital Medical University; Beijing China

6. National Center for Clinical Medical Research of Digestive Diseases; Beijing China

Funder

National Institutes of Health

National Science Foundation

Publisher

Wiley

Subject

Cell Biology,Molecular Medicine

Reference46 articles.

1. The chemical basis of morphogenesis;Turing;Philos T Roy Soc B,1952

2. Functional organization of the human 4D Nucleome;Chen;Proc Natl Acad Sci USA,2015

3. From morphogen to morphogenesis and back;Gilmour;Nature,2017

4. Emergence of function from coordinated cells in a tissue;Rajapakse;Proc Natl Acad Sci USA,2017

5. Mathematics of the genome;Rajapakse;Found Comput Math,2017

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