Intranasal administration of Acinetobacter lwoffii in a murine model of asthma induces IL ‐6‐mediated protection associated with cecal microbiota changes

Author:

Alashkar Alhamwe Bilal123ORCID,Gao Zhan4ORCID,Alhamdan Fahd156ORCID,Harb Hani178ORCID,Pichene Matthieu9,Garnier Abel9,El Andari Jihad10ORCID,Kaufmann Andreas11,Graumann Peter L.10ORCID,Kesper Dörthe1,Daviaud Christian9,Garn Holger6ORCID,Tost Jörg9ORCID,Potaczek Daniel P.1612ORCID,Blaser Martin J.4ORCID,Renz Harald1ORCID

Affiliation:

1. Institute of Laboratory Medicine, member of the German Center for Lung Research (DZL) and the Universities of Giessen and Marburg Lung Center (UGMLC) Philipps‐University Marburg Marburg Germany

2. Institute for Tumor Immunology, Clinic for Hematology, Oncology and Immunology, Center for Tumor Biology, and Immunology (ZTI) Philipps University Marburg Marburg Germany

3. College of Pharmacy International University for Science and Technology (IUST) Daraa Syria

4. Center for Advanced Biotechnology and Medicine Rutgers University Piscataway New Jersey USA

5. Department of Medicine, Pulmonary and Critical Care Medicine, Brigham and Women's Hospital Harvard Medical School Boston Massachusetts USA

6. Translational Inflammation Research Division & Core Facility for Single Cell Multiomics, member of the German Center for Lung Research (DZL) and the Universities of Giessen and Marburg Lung Center (UGMLC) Philipps‐University Marburg Marburg Germany

7. Institute for Medical Microbiology and Virology Technical University Dresden Dresden Germany

8. Department of Psychosomatic Medicine and Psychotherapy, Psychoneuroimmunology Laboratory Justus‐Liebig University Giessen Giessen Germany

9. The Laboratory for Epigenetics and Environment, Centre National de Recherche en Genomique Humaine CEA–Institut de Biologie Francois Jacob, Université Paris‐Saclay Evry France

10. SYNMIKRO, LOEWE Center for Synthetic Microbiology and Department of Chemistry Philipps‐University Marburg Marburg Germany

11. Institute for Immunology Philipps‐University Marburg Marburg Germany

12. Bioscientia MVZ Labor Mittelhessen GmbH Gießen Germany

Funder

National Institutes of Health

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

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