Adult hemiconvulsive hemiatrophy syndrome: a novel clinicoradiologic disorder in adults

Author:

Kam Ian1ORCID,Phatouros Constantine2,Prentice David3ORCID,Kho Lay K.1,Parizel Paul4

Affiliation:

1. Neurology Department Royal Perth Hospital Perth Western Australia Australia

2. Neurological Intervention and Imaging Service of Western Australia (NIISwa) Sir Charles Gairdner Hospital Perth Western Australia Australia

3. Neurology Department Perron Institute for Neurological and Translational Science Nedlands Western Australia Australia

4. The University of Western Australia (M570) Perth Western Australia Australia

Abstract

AbstractThe association of focal motor seizures with cerebral hemiatrophy is a recognised rare paediatric syndrome known as ‘hemiconvulsion, hemiatrophy and epilepsy’ (HHE). To date, HHE has not been reported in adults. We present four adult patients with striking similarities to HHE, following alcohol withdrawal in chronic alcoholics. We document the imaging findings in the acute and subacute phases, discuss the underlying mechanisms and present a hypothesis regarding the pathophysiology.

Publisher

Wiley

Subject

Internal Medicine

Reference16 articles.

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