Building evidence on safety of endovascular thrombectomy for patients under anticoagulation with vitamin K antagonists

Author:

Gao Li1ORCID,Sun Xiaowei2,Li Peiying23ORCID

Affiliation:

1. Department of Neurology, Ren Ji Hospital Shanghai Jiao Tong University School of Medicine Shanghai China

2. Clinical Research Center, Ren Ji Hospital Shanghai Jiao Tong University School of Medicine Shanghai China

3. Department of Anesthesiology, Ren Ji Hospital Shanghai Jiao Tong University School of Medicine Shanghai China

Abstract

AbstractA recent study by Brian Mac Grory and colleagues investigated the safety of endovascular thrombectomy (EVT) among patients under vitamin K antagonists (VKAs) use within 7 days prior to hospital admission. Through this retrospective, observational cohort study, they found prior VKA use did not increase the risk of symptomatic intracranial hemorrhage (sICH) overall. However, recent VKA use with a presenting international normalized ratio (INR) > 1.7 was associated with a significantly increased risk of sICH. Future large‐scale randomized controlled trials should be conducted to further clarify the effects and feasibility of EVT therapy in ischemic stroke patients under anticoagulation.

Funder

National Natural Science Foundation of China

Innovative Research Team of High-level Local University in Shanghai

Publisher

Wiley

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