Responsiveness to oral prednisolone in severe asthma is related to the degree of eosinophilic airway inflammation

Author:

Sousa A. R.1,Marshall R. P.1,Warnock L. C.1,Bolton S.2,Hastie A.3,Symon F.2,Hargadon B.2,Marshall H.2,Richardson M.2,Brightling C. E.2,Haldar P.2,Milone R.1,Chalk P.4,Williamson R.1,Panettieri R.5,Knowles R.4,Bleecker E. R.3,Wardlaw A. J.2ORCID

Affiliation:

1. GlaxoSmithKline Stevenage; Stevenage UK

2. Institute for Lung Health; Department of Infection Immunity and Inflammation; University of Leicester; Respiratory Biomedical Research Unit University Hospitals of Leicester NHS Trust; Leicester UK

3. Center for Genomics & Personalized Medicine; Section of Pulmonary & Critical Care Medicine; Wake Forest School of Medicine; Medical Center Blvd.; Winston-Salem NC USA

4. Knowles Consulting; Stevenage UK

5. Rutgers; the State University of New Jersey; New Jersey USA

Funder

GlaxoSmithKline

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Reference27 articles.

1. Pathogenesis of asthma;Holgate;Clin Exp Allergy,2008

2. Adherence in severe asthma;Bourdin;Clin Exp Allergy,2012

3. The relationship between clinical outcomes and medication adherence in difficult-to-control asthma;Murphy;Thorax,2012

4. Phenotyping airways disease: an A to E approach;Gonem;Clin Exp Allergy,2012

5. What is severe asthma?;Blakey;Clin Exp Allergy,2012

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