Examining need and capacity for the development of a pediatric liver transplantation program in Kenya

Author:

Muncner Susan1ORCID,Dell Angela J.2ORCID,Mwita Clifford34ORCID,Bigam David1ORCID,Saleh Abdullah15ORCID

Affiliation:

1. Department of Surgery University of Alberta Edmonton Alberta Canada

2. Department of Surgery University of Cape Town Health Sciences Faculty, Groote Schuur Hospital, Observatory Cape Town South Africa

3. Afya Research Africa Nairobi Kenya

4. Department of Surgery Gatundu Level 5 Hospital Gatundu Kenya

5. Office of Global Surgery University of Alberta Edmonton Alberta Canada

Abstract

AbstractBackgroundIn Africa, pediatric liver transplantation (PLT) is currently only performed in Egypt and South Africa, leaving those who require treatment in Kenya to travel abroad. The aim of this study was to determine whether sufficient capacity and need exists in Kenya to establish a safe and sustainable PLT program.MethodsA descriptive analysis of the intensive care unit (ICU) beds, surgical workforce, current hepatobiliary volume, and estimated prevalence of pediatric liver disease (PLD) was conducted across 17 hospitals in Kenya between July and September 2020. Data were collected from medical superintendents, directors of surgical departments, or nominated proxies at Kenyan Level 5 and 6 hospitals via a web‐based survey.ResultsA total of 165 ICU beds were reported at 17 facilities, with 15 facilities reporting five or more beds. About 39% of general surgeons at responding hospitals performed hepatobiliary procedures, and 30% performed pediatric surgeries. Only 10% of surgeons had pediatric training. Over half (57%) of hospitals performed hepatobiliary procedures; at the maximum, 1–5 cases were performed per week including cholecystectomy to Kasai portoenterostomy and hepatectomy. Across 13 hospitals, there were an estimated 192–570 cases of PLD seen per month. The most common PLDs were hepatitis B, neonatal hepatitis, cirrhosis, and acute hepatic failure. Overall, two hospitals possessed the minimum workforce and resources to attempt PLT.ConclusionsIn Kenya, ICU bed availability, pediatric surgical training, and hepatobiliary volume are limited. However, the high prevalence of PLD demonstrated a significant need for PLT across all Kenyan hospitals.

Funder

University of Alberta

Publisher

Wiley

Subject

Transplantation,Pediatrics, Perinatology and Child Health

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Acute liver failure in low-income and middle-income countries;The Lancet Gastroenterology & Hepatology;2023-11

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