Detection of severe congenital heart defects in live‐born infants in Norway 2017–2020

Author:

Wik Gunnar12ORCID,Jortveit Jarle3,Sitras Vasilis4,Perminow Karl Viktor1,Pripp Are Hugo5,Døhlen Gaute1,Rønnestad Arild67,Holmstrøm Henrik17

Affiliation:

1. Department of Paediatric Cardiology Oslo University Hospital Oslo Norway

2. Department of Paediatric and Adolescent Medicine, Sorlandet Hospital Kristiansand Norway

3. Department of Cardiology, Sorlandet Hospital Arendal Norway

4. Department of Obstetrics and Gynaecology, Fetal Medicine Unit Oslo University Hospital Oslo Norway

5. Oslo Centre of Biostatistics and Epidemiology, Research Support Services Oslo University Hospital Oslo Norway

6. Department of Neonatal Intensive Care Oslo University Hospital Oslo Norway

7. Institute of Clinical Medicine, University of Oslo Oslo Norway

Abstract

AbstractAimThe aims of this nationwide retrospective cohort study were to determine the time and causes of detection of severe congenital heart defects (CHDs) in live‐born infants in Norway between 2017 and 2020.MethodsInformation regarding live‐born infants with severe CHDs was retrieved from national registries and medical records.ResultsA total of 219 776 infants were born in Norway from 01.01.2017 to 31.12.2020. Severe CHDs were diagnosed in 442 (0.2%) infants. Of these, 376 (85%) infants were diagnosed either prenatally (n = 203, 46%) or before discharge from hospital after birth (n = 173, 39%). A total of 56 (13%) infants were discharged with undetected CHDs. Time of detection was unknown in 10 cases (2%). The most frequent undetected CHDs at discharge were coarctation of the aorta/aortic arch hypoplasia (n = 24), atrioventricular septal defect (n = 13), anomalous pulmonary venous connection (n = 5) and coronary artery anomalies (n = 4). Seven (13%) children with undetected CHD experienced circulatory collapse out of hospital.ConclusionMost infants with severe CHDs in Norway were identified prior to hospital discharge. However, some infants were discharged undiagnosed. Awareness of undetected CHDs and immediate cardiac assessment in infants with signs of circulatory failure early in life are still important.

Publisher

Wiley

Subject

General Medicine,Pediatrics, Perinatology and Child Health

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