Targeting metabolism to reverse T‐cell exhaustion in chronic viral infections
Author:
Affiliation:
1. The Jackson Laboratory Bar Harbor MEUSA
2. Graduate School of Biomedical Sciences and Engineering University of Maine Orono MEUSA
3. Graduate School of Biomedical Sciences Tufts University School of Medicine Boston MA USA
Funder
National Cancer Institute
Jackson Laboratory
Publisher
Wiley
Subject
Immunology,Immunology and Allergy
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1111/imm.13238
Reference100 articles.
1. Exhaustion of Activated CD8 T Cells Predicts Disease Progression in Primary HIV-1 Infection
2. Intrahepatic CD8+ T-cell failure during chronic hepatitis C virus infection
3. Impaired Effector Function of Hepatitis C Virus-Specific CD8+T Cells in Chronic Hepatitis C Virus Infection
4. Molecular Signature of CD8+ T Cell Exhaustion during Chronic Viral Infection
5. Bioenergetic Insufficiencies Due to Metabolic Alterations Regulated by the Inhibitory Receptor PD-1 Are an Early Driver of CD8 + T Cell Exhaustion
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