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Bacterial DNA Containing Methylated CpG Motifs Retains Immunostimulatory Activity in Synergy with Modified Lipopolysaccharides

  • Published:2007-02 Issue:2 Volume:51 Page:211-222
  • ISSN:0385-5600
  • Container-title:Microbiology and Immunology
  • language:en
  • Short-container-title:Microbiology and Immunology

Author:

Cho Yang Je12,Ahn Bo Young2,Song Eun Sun3,Park Shin Ae3,Lee Dong Hyeon4,Kim Doo-Sik1,Lee Na Gyong3

Affiliation:

1. Department of Biochemistry, College of Science; Yonsei University; Seoul 120-749 Korea

2. R & D Center, EyeGene Inc.; Seoul 120-113 Korea

3. Department of Bioscience and Biotechnology, Institute of Bioscience; Sejong University; Seoul 143-747 Korea

4. Department of Urology, College of Medicine; Ewha Womans University; Seoul 120-750 Korea

Publisher

Wiley

Subject

Virology,Immunology,Microbiology

Reference45 articles.

1. Toll-like receptors: critical proteins linking innate and acquired immunity;Akira;Nat. Immunol.,2001

2. Induction of NK activity in murine and human cells by CpG motifs in oligodeoxynucleotides and bacterial DNA;Ballas;J. Immunol.,1996

3. DNA activates human immune cells through a CpG sequence-dependent manner;Bauer;Immunology,1999

4. Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition;Bauer;Proc. Natl. Acad. Sci. U.S.A.,2001

5. Endotoxin, toll-like receptor 4, and the afferent limb of innate immunity;Beutler;Curr. Opin. Microbiol.,2000
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