Possible role of CYP2B6 genetic polymorphisms in ifosfamide-induced encephalopathy: report of three cases-Reference-Cited by-同舟云学术

Possible role of CYP2B6 genetic polymorphisms in ifosfamide-induced encephalopathy: report of three cases

Published:2018-01-25 Issue:3 Volume:32 Page:337-342
ISSN:0767-3981
Container-title:Fundamental & Clinical Pharmacology
language:en
Short-container-title:Fundam Clin Pharmacol

Author:

Duflot Thomas¹²^ORCID,Marie-Cardine Aude³,Verstuyft Céline⁴,Filhon Bruno³,Pereira Tony¹,Massy-Guillemant Nathalie¹,Joannidès Robinson¹²,Bellien Jérémy¹²,Lamoureux Fabien¹²

Affiliation:

1. Department of Pharmacology; Rouen University Hospital; 1 rue de Germont F 76000 Rouen France

2. Normandie Univ; UNIROUEN; Inserm U1096; Rouen University; 22 boulevard Gambetta F 76000 Rouen France

3. Department of Pediatric Hematology and Oncology; Rouen University Hospital; 1 rue de Germont F 76000 Rouen France

4. Service de Genetique moleculaire, Pharmacogenetique et Hormonologie; CHU Bicêtre; AP-HP; 78 rue du Général Leclerc 94275 Le Kremlin Bicêtre Cedex France

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/fcp.12345/fullpdf

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3. Stereoselective metabolism of ifosfamide by human P-450s 3A4 and 2B6. Favorable metabolic properties of R-enantiomer;Roy;Drug Metab. Dispos.,1999

4. Enantioselective metabolism and cytotoxicity of R-ifosfamide and S-ifosfamide by tumor cell-expressed cytochromes P450;Chen;Drug Metab. Dispos.,2005

5. 2-Chloroacetaldehyde-induced cerebral glutathione depletion and neurotoxicity;Sood;Br. J. Cancer,1996

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