Factors affecting lymphocyte collection efficiency for the manufacture of chimeric antigen receptor T cells in adults with B‐cell malignancies

Author:

Tuazon Sherilyn A.123ORCID,Li Ang134,Gooley Theodore1,Eunson Thomas W.1,Maloney David G.123,Turtle Cameron J.123,Linenberger Michael L.134,Connelly‐Smith Laura S.134

Affiliation:

1. Fred Hutchinson Cancer Research CenterClinical Research Division Seattle Washington

2. University of WashingtonDepartment of Medicine, Division of Oncology Seattle Washington

3. Seattle Cancer Care Alliance Seattle Washington

4. University of WashingtonDepartment of Medicine, Division of Hematology Seattle Washington

Funder

National Institutes of Health

National Cancer Institute

Celgene

National Heart, Lung, and Blood Institute

Publisher

Wiley

Subject

Hematology,Immunology,Immunology and Allergy

Reference19 articles.

1. Axicabtagene Ciloleucel CAR T-Cell Therapy in Refractory Large B-Cell Lymphoma

2. FDA approves CAR‐T cell therapy to treat adults with certain types of large B‐cell lymphoma [monograph on the Internet]. 2017. Available from:https://www.fda.gov/newsevents/newsroom/pressannouncements/ucm581216.htm.

3. Tisagenlecleucel in Children and Young Adults with B-Cell Lymphoblastic Leukemia

4. Chimeric Antigen Receptor T Cells in Refractory B-Cell Lymphomas

5. FDA approval brings first gene therapy to the United States [monograph on the Internet]. 2017. Available from:https://www.fda.gov/newsevents/newsroom/pressannouncements/ucm574058.htm

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