p53 activated by AND gate genetic circuit under radiation and hypoxia for targeted cancer gene therapy-Reference-Cited by-同舟云学术

p53 activated by AND gate genetic circuit under radiation and hypoxia for targeted cancer gene therapy

Published:2015-09 Issue:9 Volume:106 Page:1163-1173
ISSN:1347-9032
Container-title:Cancer Science
language:en
Short-container-title:Cancer Sci

Author:

Ding Miao¹,Li Rong²,He Rong³,Wang Xingyong³,Yi Qijian¹,Wang Weidong⁴

Affiliation:

1. Department of Cardiology Children Hospital Chongqing Medical University ChongqingChina

2. Institute of Combined Injury State Key Laboratory of Trauma, Burns and Combined Injury Chongqing Engineering Research Center for Nanomedicine College of Preventive Medicine Third Military Medical University ChongqingChina

3. Department of Emergency Children Hospital Chongqing Medical University ChongqingChina

4. Department of Radiation Oncology Tumor Hospital of Sichuan Chengdu Sichuan China

Funder

Chongqing Municipal Natural Science Foundation Program

National Natural Science Fund of China

Publisher

Wiley

Subject

Cancer Research,Oncology,General Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/cas.12739

Reference37 articles.

1. Radiation Therapy—Activation of Gene Transcription and the Development of Genetic Radiotherapy: Therapeutic Strategies in Oncology

2. Reactive oxygen intermediates target CC(A/T)6GG sequences to mediate activation of the early growth response 1 transcription factor gene by ionizing radiation.

3. Enhanced efficacy of radiation-induced gene therapy in mice bearing lung adenocarcinoma xenografts using hypoxia responsive elements

4. Cisplatin-controlled p53 gene therapy for human non-small cell lung cancer xenografts in athymic nude mice via the CArG elements

5. The radiation dose-regulated AND gate genetic circuit, a novel targeted and real-time monitoring strategy for cancer gene therapy

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