The effect of the molecular weight of polyethylene glycol on the bioavailability of paracetamol-polyethylene glycol solid dispersions-Reference-Cited by-同舟云学术

The effect of the molecular weight of polyethylene glycol on the bioavailability of paracetamol-polyethylene glycol solid dispersions

Published:1986-02 Issue:2 Volume:38 Page:126-128
ISSN:2042-7158
Container-title:Journal of Pharmacy and Pharmacology
language:en
Short-container-title:

Author:

Vila-Jato José L¹,Blanco José¹,Alonso M José¹

Affiliation:

1. Departamento de Farmacia Galénica, Facultad de Farmacia, Universidad de Santiago de Compostela, Santiago de Compostela, Spain

Abstract

Abstract A controlled study of the bioavailability of paracetamol in solid dispersion with PEG 6000, 10000 and 20000 has been made. The total amount of paracetamol excreted in urine increased with molecular weight of the PEG, but the rate of absorption of the drug was unaffected.

Publisher

Oxford University Press (OUP)

Subject

Pharmaceutical Science,Pharmacology

Link

http://academic.oup.com/jpp/article-pdf/38/2/126/37552393/j.2042-7158.1986.tb04525.x.pdf

Reference17 articles.

1. Bioavailability Studies of Acetaminophen and Nitrofurantoin

2. Theory of the mean absorption time, an adjunct to conventional bioavailability studies

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