Up-regulation of P-glycoprotein reduces intracellular accumulation of beta amyloid: investigation of P-glycoprotein as a novel therapeutic target for Alzheimer's disease
Author:
Affiliation:
1. Department of Basic Pharmaceutical Sciences, College of Pharmacy, University of Louisiana at Monroe, Monroe, LA, USA
2. Cell Biology and Bioimaging Core, Pennington Biomedical Research Center, Baton Rouge, LA, USA
Abstract
Publisher
Oxford University Press (OUP)
Subject
Pharmaceutical Science,Pharmacology
Link
http://academic.oup.com/jpp/article-pdf/63/8/1111/36356870/j.2042-7158.2011.01309.x.pdf
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4. P-glycoprotein deficiency at the blood-brain barrier increases amyloid-beta deposition in an Alzheimer disease mouse model;Cirrito;J Clin Invest,2005
5. Deposition of Alzheimer's beta-amyloid is inversely correlated with P-glycoprotein expression in the brains of elderly non-demented humans;Vogelgesang;Pharmacogenetics,2002
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