Leukoencephalopathy with transient splenial lesions related to 5‐fluorouracil or capecitabine

Author:

Perrain Valentine1ORCID,Bihan Kevin23,Bompaire Flavie34,Houillier Caroline1,Jomier Fanny5,Leclercq Delphine6ORCID,Combret Sandrine7,Mahé Julien8,Ricard Damien34,Berzero Giulia19,Psimaras Dimitri13

Affiliation:

1. AP‐HP Hôpitaux Universitaires La Pitié Salpêtrière ‐ Charles Foix Service de Neurologie 2‐Mazarin Sorbonne UniversitéInsermCNRSUMR S 1127Institut du Cerveau et de la Moelle épinièreICM Paris France

2. Regional Pharmacovigilance Center Department of Pharmacology Pitié‐Salpêtrière Hospital Paris France

3. OncoNeuroTox Group Center for Patients with Neurological Complications of Oncologic Treatments Hôpitaux Universitaires Pitié‐Salpêtrière‐Charles Foix et Hôpital Percy Paris France

4. Department of Neurology Service de Santé des Armées Hôpital d'Instruction des Armées Percy Clamart France

5. Service de Neurologie Hôpital Saint Joseph Paris France

6. Service de Neuroradiologie AP‐HPGroupe Hospitalier Pitié‐Salpêtrière Paris France

7. Department of Pharmacology Regional Pharmacovigilance Center Dijon France

8. Department of Pharmacology Regional Pharmacovigilance Center Nantes France

9. Neurology Unit IRCCS San Raffaele Scientific Institute Milan Italy

Publisher

Wiley

Subject

Neurology (clinical),Neurology

Reference45 articles.

1. Clinical Pharmacology of 5-Fluorouracil

2. Posterior reversible encephalopathy syndrome following chemotherapy with oxaliplatin and a fluoropyrimidine: A case report and literature review

3. Capecitabine-Induced Cerebellar Toxicity

4. Capecitabine-Related Neurotoxicity Presenting as Trismus

5. Xeloda product information [Internet]. [cited 2021 Feb 1]. Available from:https://www.ema.europa.eu/en/documents/product‐information/xeloda‐epar‐product‐information_en.pdf.

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